July 2025 HCPCS Update: These Codes will Cost You

Kara Wily, Business Development Strategist and author at Human Medical Billing, smiling in professional attire.
Reviewed for compliance and accuracy by Ramesh (Chetty) Jayakumar, M.B.A., Healthcare Strategy Leader with 23+ years leading U.S. medical billing, RCM compliance, and provider reimbursement operations - Authored by Kara Wily, Business Development Strategist with 10+ years helping healthcare practices optimize billing workflows and coding adoption, on April 24, 2025
Concerned doctor reacting to July 2025 HCPCS code updates, branded by Human Medical Billing.

Attention SNFs and Medical Billers: Significant Changes Ahead!

If you’re an Skilled Nursing Facility (SNF), Medicare is once again altering the rules. There’s a huge July 2025 HCPCS update you can’t afford to miss.

Why is this significant?

  • Apply the wrong code? Your application will be DENIED.
  • Utilizing an outdated code? You lose money.
  • Miss a new code? You may miss THOUSANDS in reimbursements.

What is the HCPCS Update effective July 2025?

The July 2025 HCPCS update is a significant update introduced by CMS (Centers for Medicare & Medicaid Services). The updates alter the way SNFs like yours bill for:

  • Drugs
  • Imaging procedures
  • Cancer therapies
  • Prosthetics
  • And more…

CMS adds new codes, supplants some current codes, and removes others.

Effective Date: July 1, 2025
Implementation begins: July 7, 2025.

Real Talk: What Happens If You Ignore This?

What You DoWhat Happens
Use a discontinued codeClaim is denied
Use an old descriptionCompliance issue
Don’t train your teamLost revenue
Use new codes correctlyMaximum reimbursement

NEW Codes = NEW MONEY

Let’s look at the shiny new codes from the July 2025 HCPCS update.

Category: Imaging & Cancer Planning

CodeWhat It MeansWhy It Matters
C8004Angiogram simulation for tumor planningBig for cancer surgery prep

Category: Chemotherapy

CodeWhat It MeansWhy It Matters
J9161Denileukin Diftitox-CXDL (new immunotherapy drug)High reimbursement

Category: Diagnostic Imaging

CodeWhat It MeansWhy It Matters
A9611Flurpiridaz F18 for PET scansFor heart disease imaging

Category: Blood Disorders

CodeWhat It MeansWhy It Matters
C9304Marstacimab for HemophiliaImportant for clotting factor billing

Category: Custom Prosthetics

CodeDescription
L5827Knee-shin system with electromechanical control
L6028–L6037Modular partial hand prosthetics
L6700Myoelectric-controlled upper prosthetics

Why it matters: These codes now allow for SNFs that provide rehab services to bill for advanced devices.

Discontinued Codes = Do NOT Use

You’ll get denied for using these after July 1.

CodeDescription
Q5139Eculizumab-AEEB (10 mg)
J9247Melphalan Flufenamide
L8010Breast prosthesis, mastectomy sleeve

Replace these NOW! Don’t say we didn’t warn you.

Revised Codes = Be Extra Careful

Some codes got updated descriptions or changed dosages.

Old CodeNew CodeKey Change
Q5139Q5152Dosage changed to 2 mg
J9247TerminatedNo replacement yet

How to Prepare for the July 2025 HCPCS Update

Infographic outlining HCPCS update implementation steps by Human Medical Billing, including code identification, training, and compliance.

1. Verify Your Claims Immediately

Verify whether you are still using them:

  • Q5139
  • J9247
  • L8010

If so, correct them right away.

2. Update Your Billing Software & EHR

Call your supplier and ask:

“Do we possess the new codes from the July 2025 HCPCS update within our system?”

3. Train Your Employees

Schedule a 30-minute meeting with your employees prior to July 1.

Use flashcards, in-class demonstrations

4. Look for Crosswalks

Some deleted codes have direct replacements.

Common Errors That Can Cost You a Fortune

  • Not updating the software
  • Without new code descriptions.
  • Filing claims with July 2024 codes
  • Trusting memory rather than referencing the list

FAQ: You Ask, We Answer

Yes! If you are charging Medicare for any service, these codes are for you.

Claim will be denied. You can reprocess, but that postpones payment weeks later.

Every three months. July is the largest update of the year.

Final Thoughts: Be Prepared and Not Surprised

The July 2025 HCPCS update is the year’s largest billing revision.

If you do nothing, you’ll have denied claims, lost business, and a whole lot of stress.

But what if you take action now?

  • You stay compliant
  • You charge correctly.
  • You get paid fast

One More Time - Here's What You Need to Do:

  • Read the update
  • Train your team
  • Double-check every code
  • Bookmark this blog
  • Take a help from experts like Human Medical Billing
Smiling doctor highlighting simplified medical billing services in California with guaranteed claim denial reduction – Human Medical Billing
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Human Medical Billing

Human Medical Billing, based in Ventura, California, is a trusted U.S. provider of medical billing, coding compliance, and revenue cycle management services. With over a two decade of hands-on experience, we help healthcare providers improve reimbursement accuracy, reduce denials, and stay aligned with HIPAA and CMS guidelines. Every article we publish reflects our direct operational expertise in billing strategy, regulatory updates, and U.S. payer requirements—ensuring providers receive accurate, actionable insights.

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